International Journal of Basic and Applied Physiology

Polycystic ovary syndrome (PCOS), the commonest cause of infertility, is a heterogeneous syndrome with a significant alteration in autonomic modulation in the form of increased adrenergic drive and a depressed vagal activity. The various co-morbidities associated with PCOS such as obesity, insulin resistance, dyslipidemia, hyperandrogenism and altered thyroid profile, are known to cause significant alteration in autonomic dysfunctions. Assessment of autonomic functions has proved to be a sensitive tool in diagnosing the early features of CV dysfunction in PCOS. When detected early, it enables an early intervention to yield a better cardiovascular health to these patients. The simplest approach of restoring the sympathovagal balance would be the life style modifications in the form of regular exercise and practice of yoga. Regular exercise decreases adiposity and improves the sensitivity of insulin in the peripheral tissues and yoga improves general cardiovascular health. Thus, these alternative therapies can supplement the medical therapy advocated to these patients and would lead to better outcome in both reproductive and cardiovascular health.